Genetics study develops our understanding of alcohol use disorder

Interesting news for future potential treatments of alcohol use disorder:  a study in PNAS recently came out that points to a novel gene, and particular hormone, being involved in drinking behavior, β-Klotho and FGF21, respectively.  This is particularly interesting because it elaborates on our existing understanding of alcohol use disorder, and may offer a new molecular target for medications to disrupt drinking behavior.  The mainstay of substance use disorder treatment is a combination of psychosocial (such as psychotherapy and/or 12 step meetings, lifestyle changes) and biological treatments (like existing medications including naltrexone/vivitrol, acamprosate, disulfiram/antabuse).  With the current array of medications available, one--or a combination of several--works well for many folks, but more options, with potentially a better side effect profile, is always welcome.  

NBC story: http://www.nbcnews.com/health/health-news/gene-might-affect-how-much-you-drink-n689156

Article: http://www.pnas.org/content/early/2016/11/22/1611243113.abstract